This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain).
The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes.
This gene exhibits a gonad-specific and sexually dimorphic expression pattern.
Defective testicular development and XY feminization occur when this gene is hemizygous.
Applications:Suitable for use in Western Blot, ELISA
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:Human
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu
Immunogen:DMRT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 295-322 amino acids from the C-terminal region of human DMRT1.