This gene encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway.
The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/NRSF and REST4.
Mutations in this gene have been linked to progressive myoclonus epilepsy.
Alternate splicing results in multiple transcript variants.
A pseudogene of this gene is found on chromosome 3.
Applications:Suitable for use in Western Blot, ELISA
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity：Human
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：PRICKLE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic between 677-704 amino acids selected from the C-terminal region of human PRICKLE1.
