Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs.
During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs.
The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein.
The encoded protein belongs to the TOP6A protein family.
Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described.
Applications:Suitable for use in Western Blot, ELISA
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity：Human
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：SPO11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 298-326 amino acids from the C-terminal region of human SPO11.
