84-1286-05 IQCB1, ID (IQCB1, KIAA0036, NPHP5, IQ calmodulin-binding motif-containing protein 1, Nephrocystin-5, p53 and DNA damage-regulated IQ motif protein) 200ul 037080
84-1286-05 IQCB1, ID (IQCB1, KIAA0036, NPHP5, IQ calmodulin-binding motif-containing protein 1, Nephrocystin-5, p53 and DNA damage-regulated IQ motif protein) 200ul 037080
This gene encodes a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein.
The encoded protein has a central coiled-coil region and two calmodulin-binding IQ domains.
It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells.
The protein is thought to play a role in ciliary function.
Defects in this gene result in Senior-Loken syndrome type 5.
Alternative splicing results in multiple transcript variants.
Applications:Suitable for use in Western Blot and ELISA.
Other applications have not been tested.
Recommended Dilutions:Western Blot: 1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity：Recognizes human IQCB1.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 384-411 in the central region of human IQCB1, UniProt Accession #Q15051.
