This gene encodes a protein containing a potential clathrin-binding motif, consensus dileucine signals, and tyrosine-based sorting signals for targeting to vesicles of lysosomal lineage.
The encoded protein may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes.
Mutations in this gene are associated with Hermansky-Pudlak syndrome type 3.
Alternate splice variants exist, but their full length sequence has not been determined.
[provided by RefSeq].
Applications:Suitable for use in Western Blot, ELISA
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity：Human
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：HPS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-290 amino acids from the N-terminal region of human HPS3.
