This gene encodes an RGD-containing protein that binds to type I, II and IV collagens.
The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins.
This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage.
The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion.
Mutations in this gene are associated with multiple types of corneal dystrophy.
Applications:Suitable for use in Western Blot, Indirect Flow Cytometry and ELISA
Other applications have not been tested.
Recommended Dilutions:Western Blot: 1:1000Indirect Flow Cytometry: 1:10-1:50Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A and peptide affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:Recognizes human TGFBI.
Isotype:IgG
Calc Applications Abbrev:E FC WB
Calc Crossreactivity:Hu
Immunogen:KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 106-135 amino acids from the N-terminal region of human TGFBI. Species Sequence Homology: bovine, mouse, porcine