This gene encodes a member of the cytoplasmic polyadenylation element (CPE) binding protein family.
This highly conserved protein binds to a specific RNA sequence called the CPE found in the 3' UTR of some mRNAs.
Similar proteins in Xenopus and mouse function to induce cytoplasmic polyadenylation of dormant mRNAs with short polyA tails, resulting in their translation.
Members of this protein family regulate translation of cyclin B1 during embryonic cell divisions.
Multiple transcript variants encoding different isoforms have been found for this gene.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilutions:Western Blot: 1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A and peptide affinity chromatography
Form:Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide
Specificity:Recognizes human CPEB1.
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu
Immunogen:KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 447-475 in the C-terminal region of human CPEB1. Species Sequence Homology: Xenopus, zebrafish, mouse and rat