Syntenin 2 binds to the cytoplasmic domains of the syndecans: it contains a tandem repeat of PDZ domains that reacts with the FYA (phe-tyr-ala) C-terminal amino acid sequence of the syndecans.
Cells that overexpress the fusion protein show numerous cell surface extensions, suggesting that Syntenin 2 may have an effect on cytoskeleton-membrane organization.
Therefore, Syntenin 2 may function as an adaptor that couples syndecans to cytoskeletal proteins or cytosolic downstream signal-effectors.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity：Recognizes human SDCBP2.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 98-127 in the N-terminal region of human SDCBP2, UniProt Accession #Q9H190.
