84-1280-19 MDS1, ID (MECOM, MDS1, MDS1 and EVI1 complex locus protein MDS1, Myelodysplasia syndrome 1 protein, Myelodysplasia syndrome-associated protein 1) 200ul 038304
84-1280-19 MDS1, ID (MECOM, MDS1, MDS1 and EVI1 complex locus protein MDS1, Myelodysplasia syndrome 1 protein, Myelodysplasia syndrome-associated protein 1) 200ul 038304
MDS1 is located at 3q26 170-400 kb upstream (telomeric) of EVI1 in the chromosomal region in which some of the breakpoints 5' of EVI1 have been mapped.
MDS1 has been identified as a single gene as well as a previously unreported exon (s) of EVI1.
MDS1 exists in normal tissues both as a unique transcript and as a normal fusion transcript with EVI1, with an additional 188 codons at the 5' end of the previously reported EVI1 open reading frame.
In cells with translocation t (3;21), additional fusion transcripts are AML1-MDS1 and AML1-MDS1-EVI1.
EVI1 and MDS1 are involved in leukemia associated with chromosomal translocation breakpoints in the region between these genes.
Applications:Suitable for use in Western Blot, ELISA
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity：Mouse
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Mo
Immunogen：MDS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80-109 amino acids from the Central region of human MDS1.
