ISL1 is a member of the LIM/homeodomain family of transcription factors.
The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression.
The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation.
Mutations in this gene have been associated with maturity-onset diabetes of the young.
Applications:Suitable for use in Western Blot and ELISA.
Other applications have not been tested.
Recommended Dilutions:Western Blot: 1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A and peptide affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity：Recognizes human ISL1. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo
Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 156-185 in the central region of human ISL1. .Species Sequence Homology: chicken, zebrafish and rat
