Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells.
Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+).
Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis.
Uses NAD(+) as acceptor (By similarity).
May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression.
Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot: 1:100-500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A and peptide affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity：Recognizes human STEAP3.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 440-470 amino acids from the C-terminal region of human STEAP3.
