This gene encodes a member of the TNF receptor associated factor (TRAF) family.
TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily.
The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation.
This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase.
This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK.
Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined.
Applications:Suitable for use in Western Blot, ELISA
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity：Human
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：TRAF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 426-455 amino acids from the C-terminal region of human TRAF4.
