This gene encodes a member of the hedgehog family of secreted signaling molecules.
Hedgehog proteins are essential regulators of a variety of developmental processes including growth, patterning and morphogenesis.
The encoded protein specifically plays a role in bone growth an differentiation.
Mutations in this gene are the cause of brachydactyly type A1 which is characterized by shortening or malformation of the phalanges.
Mutations in this gene are also the cause of acrocapitofemoral dysplasia.
Applications:Suitable for use in Western Blot, Immunohistochemistry and ELISA.
Other applications have not been tested.
Recommended Dilutions:Western Blot: 1:1000Immunohistochemistry (FFPE): 1:10-1:50Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A and peptide affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity：Recognizes human IHH.
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu
Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 51-80 in the N-terminal region of human IHH, UniProt Accession #Q14623. Species Sequence Homology: mouse
