84-1275-63　SSRP1, CT (SSRP1, FACT80, FACT complex subunit SSRP1, Chromatin-specific transcription elongation factor 80kD subunit, Facilitates chromatin transcription complex 80kD subunit, Facilitates chromatin transcription complex subunit SSRP1, Recombination signal sequence recognition protein 1, Structure-specific recognition protein 1, T160) 200ul　042332

特徴

• The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT.
• FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation.
• FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin.
• This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA.
• This protein also functions as a co-activator of the transcriptional activator p63.
• An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.
• Applications:Suitable for use in Western Blot, ELISA
• Recommended Dilution:ELISA: 1:1,000Western Blot: 1:100-500
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.