This gene encodes a member of the polycystin protein family.
The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini.
The protein may be an integral membrane protein involved in cell-cell/matrix interactions.
The encoded protein may function in renal tubular development, morphology, and function, and may modulate intracellular calcium homoeostasis and other signal transduction pathways.
This protein interacts with polycystin 1 to produce cation-permeable currents.
Mutations in this gene have been associated with autosomal dominant polycystic kidney disease.
Applications:Suitable for use in Western Blot, ELISA
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity：Mouse
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Mo
Immunogen：PKD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 873-903 amino acids from the C-terminal region of human PKD2.
