84-1271-51　TRIP10, NT (TRIP10, CIP4, STOT, STP, Cdc42-interacting protein 4, Protein Felic, Salt tolerant protein, Thyroid receptor-interacting protein 10) 200ul　043268

特徴

• Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity).
• Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis.
• Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules.
• Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex.
• Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles.
• Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells.
• May be required for the lysosomal retention of FASLG/FASL.
• Applications:Suitable for use in Western Blot, ELISA
• Recommended Dilution:ELISA: 1:1,000Western Blot: 1:100-500
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.