UBP1 functions as a transcriptional activator in a promoter context-dependent manner.
Modulates the placental expression of CYP11A1.
Involved in regulation of the alpha-globin gene in erythroid cells.
Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity).
Involved in regulation of the alpha-globin gene in erythroid cells.
Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box.
Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunofluorescence.
Other applications not tested.
Recommended Dilutions:Western Blot: 1:1000Immunohistochemistry (FFPE): 1:10-1:50Immunofluorescence: 1:10-1:50Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity：Recognizes human UBP1.
Isotype：IgG
Calc Applications Abbrev：E IF IHC WB
Calc Crossreactivity：Hu
Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 266-295 in the c-terminal region of human UBP1, UniProt Accession #Q9NZ17. Species Sequence Homology: mouse
