The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes.
The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells.
Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE).
Several transcript variants encoding different isoforms have been found for this gene.
Applications:Suitable for use in Western Blot and ELISA.
Other applications have not been tested.
Recommended Dilution:Western Blot: 1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A and peptide affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity：Recognizes human FCGR2B.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 250-279 in the C-terminal region of human FCGR2B, UniProt Accession #P31994; NP_003992.3; NP_001002273.1; NP_001177757.1; NP_001002274.1
