Protein kinase that regulates key processes linked to cell growth and survival.
Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion.
Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics.
Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired.
Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications have not been tested.
Recommended Dilution:Western Blot: 1:1000Immunohistochemistry: 1:10-1:50Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity：Recognizes mouse Abl1.
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Mo
Immunogen：Synthetic peptide corresponding to a portion of amino acids within aa 613-641 from the Central region of human Mouse Abl1 (NP_033724), conjugated to KLH.
