This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription.
This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA.
This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.
Applications:Suitable for use in Western Blot and Immunofluorescence.
Other applications have not been tested.
Recommended Dilution:Western Blot: 1:1000Immunofluorescence: 1:10-1:50Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity：Recognizes human TOP1.
Isotype：IgG
Calc Applications Abbrev：IF WB
Calc Crossreactivity：Hu
Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids aa 2-31 in the N-terminal region of human TOP1, UniProt Accession #NP_003277.1;P11387Species sequence homology: hamster, mouse, rat
