This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex.
Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio.
Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing.
Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits.
Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized.
Applications:Suitable for use in Immunofluorescence, Western Blot, Immunohistochemistry and ELISA.
Other applications not tested.
Recommended Dilution:Immunofluorescence: 1:10-1:50Western Blot: 1:1000Immunohistochemistry (FFPE): 1:10-1:50Optimal dilution to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:Recognizes human CACNA2D2. Species Crossreactivity: mouse
Isotype:IgG
Calc Applications Abbrev:E IF IHC WB
Calc Crossreactivity:Hu Mo
Immunogen:KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 643-671 in the central region of human CACNA2D2, UniProt Accession #Q9NY47.