This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions.
ABC proteins transport various molecules across extra- and intracellular membranes.
ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White.
This gene is a member of the MRP subfamily which is involved in multi-drug resistance.
This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1.
Increased expression of this gene is associated with breast cancer.
Applications:Suitable for use in Western Blot, Immunohistochemistry, ELISA
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:mouse
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:Mouse
Isotype:IgG
Calc Applications Abbrev:E IHC WB
Calc Crossreactivity:Mo
Immunogen:ABCC12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 722-751 amino acids from the Central region of human ABCC12.