Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain.
It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane.
The complex consists of 13 mitochondrial- and nuclear-encoded subunits.
The mitochondrially-encoded subunits perform the electron transfer of proton pumping activities.
The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex.
This gene encodes the nuclear-encoded subunit Va of the human mitochondrial respiratory chain enzyme.
A pseudogene COX5AP1 has been found in chromosome 14q22.
[provided by RefSeq].
Applications:Suitable for use in Western Blot, ELISA
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:mouse
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:Mouse
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Mo
Immunogen:COX5A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human COX5A.