84-1259-78　PPARA, ID (PPARA, NR1C1, PPAR, Peroxisome proliferator-activated receptor alpha, Nuclear receptor subfamily 1 group C member 1) 200ul　040300

特徴

• Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes.
• Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism.
• The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily.
• PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses.
• Three closely related subtypes (alpha, beta/delta, and gamma) have been identified.
• This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor.
• Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined.
• Applications:Suitable for use in Western Blot, Indirect Flow Cytometry, ELISA
• Recommended Dilution:ELISA: 1:1,000Western Blot: 1:100-500Indirect Flow Cytometry: 1:10-50
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.