The ZNF146 protein is a 33 kDa Kruppel protein, composed solely of 10 zinc finger motifs.
ZNF146 overexpression in tumors may alter the balance between hRap1 and other telomeric proteins; therefore ZNF146 function may be linked to telomere regulation.
ZNF146 is strongly overexpressed in many pancreas and colorectal cancers.
Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas.
ZNF146 is overexpresseed in 80% of colorectal cancers.
Applications:Suitable for use in Western Blot, Indirect Flow Cytometry, ELISA
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity：Human, mouse
Isotype：IgG
Calc Applications Abbrev：E FC WB
Calc Crossreactivity：Hu Mo
Immunogen：ZNF146 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-54 amino acids from the N-terminal region of human ZNF146.
