Coagulation factor II (thrombin) receptor-like 2 (F2RL2) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins.
F2RL2 is also a member of the protease-activated receptor family and activated by thrombin.
F2RL2 is activated by proteolytic cleavage of its extracellular amino terminus.
The new amino terminus functions as a tethered ligand and activates the receptor.
F2RL2 is a cofactor for F2RL3 activation by thrombin.
It mediates thrombin-triggered phosphoinositide hydrolysis and is expressed in a variety of tissues.
Applications:Suitable for use in Western Blot, Immunohistochemistry, ELISA
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:Human
Isotype:IgG
Calc Applications Abbrev:E IHC WB
Calc Crossreactivity:Hu
Immunogen:F2RL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-50 amino acids from the N-terminal region of human F2RL2.