84-1254-39　MED14, ID (MED14, ARC150, CRSP2, CXorf4, DRIP150, EXLM1, RGR1, TRAP170, Mediator of RNA polymerase II transcription subunit 14, Activator-recruited cofactor 150kD component, Cofactor required for Sp1 transcriptional activation subunit 2, Mediator complex subunit 14, RGR1 homolog, Thyroid hormone receptor-associated protein complex 170kD component, Transcriptional coactivator CRSP150, Vitamin D ...　038316

特徴

• The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA.
• These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus.
• The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1.
• This protein is also a component of other multisubunit complexes e.g.
• thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
• This protein contains a bipartite nuclear localization signal.
• This gene is known to escape chromosome X-inactivation.
• Applications:Suitable for use in Western Blot, ELISA
• Recommended Dilution:ELISA: 1:1,000Western Blot: 1:100-500
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.