This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases.
The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily.
BMPs are involved in endochondral bone formation and embryogenesis.
These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD.
Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
Mutations in this gene have been associated with primary pulmonary hypertension.
Applications:Suitable for use in Western Blot, Immunohistochemistry, ELISA
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity：Human
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu
Immunogen：BMPR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 141-168 amino acids from the Central region of human BMPR1B.
