84-1252-65　XRCC5, ID (K439) (XRCC5, G22P2, X-ray repair cross-complementing protein 5, 86kD subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 2, ATP-dependent DNA helicase II 80kD subunit, CTC box-binding factor 85kD subunit, DNA repair protein XRCC5, Ku80, Ku86, Lupus Ku autoantigen protein p86, Nuclear factor IV, Thyroid-lupus autoantigen, X-ray repair complementing defective repair in Chines ...　043934

特徴

• The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5.
• Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events.
• This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination.
• A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
• Applications:Suitable for use in Western Blot, Immunofluorescence, Indirect Flow Cytometry and ELISA.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:1000Immunofluorescence: 1:10-1:50Indirect Flow Cytometry: 1:10-1:50Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.