The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family.
The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells.
This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1.
This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain.
Applications:Suitable for use in Western Blot, Indirect Flow Cytometry and ELISA.
Other applications not tested.
Recommended Dilutions:Western Blot: 1:1000Indirect Flow Cytometry: 1:10-1:50Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography
Form:Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide
Specificity:Recognizes human DUOX2
Isotype:IgG
Calc Applications Abbrev:E FC WB
Calc Crossreactivity:Hu
Immunogen:KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 513-542 in the c-terminal region of human DUOX2, UniProt Accession #Q9NRD8