Pin-1 is a the peptidylprolyl cis/trans isomerase enzyme which is responsible, as its name suggests, for flipping the proline ring from the cis to the trans conformation.
This enzyme is heavily upregulated in tumor cells, so that antibodies to this protein can be used as tumor markers.
Pin-1 protein is concentrated in the nucleus in small punctate structures and is particularly obvious in tumor cells.
The HGNC name for this protein is Pin-1.
Applications:Suitable for use in Immunocytochemistry, Immunofluorescence and Western Blot.
Other applications not tested.
Recommended Dilution:Immunocytochemistry (ABC): 1:5000Immunofluorescence: 1:500-1:1000 Western Blot: 1:10,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：chicken
Grade：Purified
Purity：Purified
Form：Supplied as a liquid in PBS, 10mM sodium azide.
Specificity：Recognizes human Pin1 in HeLa cells.
Isotype：IgY
Calc Applications Abbrev：IC IF WB
Calc Crossreactivity：Hu
Immunogen：Recombinant full length Pin-1 purified from E. coli.
