Kaposi's sarcoma-associated Herpes virus (KSHV) belongs to the gamma-(2)-Herpes virus subfamily and has been closely linked to the Kaposi’s sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman’s disease.
The genome of KSHV is 165-170kb and contains at least 88 open reading frames.
KSHV ORF8 is a virion envelope-associated protein.
Akula et al (2003) report it acts as a Glycoprotein B mediated signaling during virus entry.
This Glycoprotein possesses the Arg-Gly-Asp (RGD) motif and utilizes alpha3beta1 integrin as one of the receptors for its entry into the target cells.
Applications:Western Bloting: 1:500-1:2000
ELISA: Suggested dilution 1:10000
Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Purity：Serum
Form：Serum
Specificity：Human
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide, corresponding to amino acid sequence of KSHV ORF8.
