Src is a proto-oncogenic tyrosine kinase belonging to the Src family of non-receptor tyrosine kinases.
This proto-oncogene plays a pivotal role cellular processes such as proliferation, migration, transformation and regulation of embyronic development and cell growth.
Src tyrosine kinases transmit integrin-dependent signals for cell movement and proliferation.
The study of Src proteins have contributed to the understanding of cancer caused by abnormal cellular signaling.
Applications:Suitable for use in Western Blot and Cell Function Assay.
Other applications not tested.
Recommended Dilution:Western Blot: 5ug/mlOptimal dilutions to be determined by the researcher.
Positive Control:HEK293T cells transfected with myc-tagged Src and CBP
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in 0.1M Tris-glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
Specificity：Recognizes human Src acetylated at Lys430.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Synthetic linear peptide corresponding to human Src, acetylated at Lys430 (KLH). Species sequence homology: Mouse, rat (100%)
