Histone H2A deubiquitinase MYSM, often referred to as 2A-DUB is metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A.
2A-DUB regulates transcription by coordinating histone acetylation and deubiquitination, and destabilizing the association of linker histone H1 with nucleosomes.
The 2A-DUB mechanism may just be one of many H2A ubiquitination proteins that have the ability to regulate transcription.
2A-DUB is also essential for cell cycle progression and gene expression.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:1000 detected MYSM1 on 10ug of NIH/3T3 cell lysate
Optimal dilutions to be determined by the researcher.
Positive Control:NIH/3T3 cell lysate
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Serum
Purity：Serum
Form：Supplied as a liquid in 0.05% sodium azide.
Specificity：Recognizes human MYSM1. Species Crossreactivity: Mouse.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo
Immunogen：Recombinant protein corresponding to human MYSM1.
