Fidgetin is a AAA protein that belongs to the meitoic or subfamily-7 (SF7) group of ATPases.
These enzymes are associated with many different general cellular activities, such as but not limited to, membrane fusion, proteolysis, metabolic signaling, peroxisome biogenesis, endosome sorting, and meiotic spindle formation.
However, the specific functions and mechanisms for SF7 AAA proteins remain largely unclear.
It is reported that mutant Fidgetin is found in a mammalian developmental mutant and is suggested to play in role in embryonic development.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1ug/mlOptimal dilutions to be determined by the researcher.
Positive Control:Mouse brain tissue lysate
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by affinity chromatography.
Form:Supplied as a liquid in 0.1M Tris-glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
Specificity:Recognizes human Fidgetin. Species Crossreactivity: Mouse.
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu Mo
Immunogen:Synthetic linear peptide corresponding to human Fidgetin (KLH).