FGFR-1 is a member of the basic fibroblast growth factor family of proteins and is thought to be important in the induction and propagation of benign prostatic hyperplasia.
A shortage of FGFR-1 causes death post-implantation and has been linked to neurofascin and neurite outgrowth.
FGFR-1 expression has recently been found to be increased in patients with renal cell carcinoma and FGFR-1 may also have a role to play in early limb formation.
Applications:Suitable for use in Western Blot and Cell Function Assay.
Other applications not tested.
Recommended Dilution:Western Blot: 0.2ug/mlOptimal dilutions to be determined by the researcher.
Positive Control:Untreated and lambda phosphatase-treated HEK293T cells transfected with FGFR-1
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in 0.1M Tris-glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
Specificity：Recognizes human FGFR-1 phosphorylated at Tyr653/Tyr654.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Synthetic linear peptide corresponding to human FGFR-1 phosphorylated at Tyr653/Tyr654 (KLH). Species sequence homology: mouse, rat, chicken, bovine, xenopus and zebrafish.
