The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-DNA and protein-protein interactions.
Abundant expression of this gene was found in the testicular tissue of fertile men, but was not detected in azoospermic patients.
Studies of the mouse counterpart suggest that this gene may function as a testis specific transcription factor during spermatogenesis.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:16,000Western Blot: 1ug/ml, observed in human testis lysate on ~25-30kD bandsOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity:Recognizes human RNF141. Species sequence homology: Bovine, canine, mouse and rat.
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Bo Ca Hu Mo Rt
Immunogen:Synthetic peptide corresponding to C-LNMADEAGQPHRP, from human RNF141, at C-terminal (NP_057506.2).