Voltage-dependent anion channels (VDAC) are small pore-forming membrane proteins that regulate metabolite exchange across the mitochondrial outer membrane.
Apart from metabolite transfer, VDAC role has also been suggested during apoptosis.
VDAC2 is one of the isoforms of VDAC.
It interacts with BAK and functions as a specific inhibitor of BAK-dependent mitochondrial apoptosis.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:64,000Western Blot: 0.3-1ug/ml, observed in human heart lysates on ~32kD bandsOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity：Recognizes human VDAC2. Species sequence homology: Canine, mouse and rat.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Ca Hu Mo Rt
Immunogen：Synthetic peptide corresponding to C-DSAKSKLTRNN, from human VDAC2, at the internal region of the protein (NP_003366.2).
