This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis.
The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain.
The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions.
The gene mutations are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin.
Alternatively spliced transcript variants encoding the same protein have been identified.
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilution:ELISA: 1:64,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity：Recognizes TRIM37. Species sequence homology: Bovine, canine and human.
Isotype：IgG
Calc Applications Abbrev：E
Calc Crossreactivity：Bo Ca Hu
Immunogen：Synthetic peptide corresponding to C-EDLSFNTDENSGR, from TRIM37, at C-terminal (NP_056109.1).
