84-1232-86　TRIM3 (Tripartite Motif-containing Protein 3, Brain-expressed RING Finger Protein, RING Finger Protein 22, RING Finger Protein 97, BERP, RNF22, RNF97) 100ug　T8464-75E

特徴

• The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins.
• The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region.
• This protein localizes to cytoplasmic filaments.
• It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles.
• The rat protein can also interact with alpha-actinin-4.
• Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport.
• Alternatively spliced transcript variants encoding the same isoform have been identified.
• Applications:Suitable for use in ELISA and Western Blot.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:64,000Western Blot: 0.1-1ug/ml, mouse brain and human brain (cerebellum) observed on ~85kD bandsOptimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for at least 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.