This gene encodes a member of the serine protease family.
Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders.
This gene was identified as a gene overexpressed in pancreatic carcinoma.
The encoded protein is membrane bound with a N-terminal anchor sequence and a glycosylated extracellular region containing the serine protease domain.
Multiple transcript variants encoding different isoforms have been found for this gene.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:1000Western Blot: 1-3ug/ml, observed in human bone marrow lysates on ~48kD bandsOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity:Recognizes human TMPRSS4. Species sequence homology: Mouse.
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu Mo
Immunogen:Synthetic peptide corresponding to DSTRCNADDAYQGE, from human TMPRSS4, at the internal region of the protein (NP_063947.1, NP_001077416.1).