The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors.
The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors.
The protein is a member of the tripartite motif (TRIM) family.
The TRIM motif includes three zinc-binding domains-a RING, a B-box type 1 and a B-box type 2-and a coiled-coil region.
Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilution:ELISA: 1:32,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity：Recognizes TRIM24. Species sequence homology: Bovine and human.
Isotype：IgG
Calc Applications Abbrev：E
Calc Crossreactivity：Bo Hu
Immunogen：Synthetic peptide corresponding to C-KRLKSIEERQLLK, from TRIM24, at C-terminal (NP_056989.2, NP_003843.3).
