Thyroid hormones regulate general metabolism and normal cellular growth and development.
These actions are regulated by the thyroid hormone receptor (TR), a ligand-dependent transcriptional factor.
At least two genes and several isoforms encode TR.
Recent studies have implicated a role of TRs in thyroid hormone-induced apoptosis in larval tissues and proliferation of adult cell types.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:32,000Western Blot: 0.5-1,5ug/ml, observed in human bone marrow lysates on ~60+50kD bandsOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity：Recognizes human THRA. Species sequence homology: Bovine, canine, mouse, porcine and rat.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Bo Ca Hu Mo Po Rt
Immunogen：Synthetic peptide corresponding to C-KEEMIRSLQQRP, from human THRA, at the internal region of the protein (NP_955366.1, NP_003241.2).
