84-1232-36 TXNDC4 (Endoplasmic Reticulum Resident Protein 44, ER Protein 44, ERp44, Thioredoxin Domain-containing Protein 4, KIAA0573, ERP44, UNQ532/PRO1075) 100ug T5010-11J1
84-1232-36 TXNDC4 (Endoplasmic Reticulum Resident Protein 44, ER Protein 44, ERp44, Thioredoxin Domain-containing Protein 4, KIAA0573, ERP44, UNQ532/PRO1075) 100ug T5010-11J1
Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif.
Inhibits the calcium channel activity of ITPR1.
May have a role in the control of oxidative protein folding in the endoplasmic reticulum.
Required to retain ERO1L and ERO1LB in the endoplasmic reticulum.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:32,000Western Blot: 0.2-0.6ug/ml, observed in lysates of cell line K562 on ~47kD bandsOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity：Recognizes human TXNDC4. Species sequence homology: Bovine, mouse and rat.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Bo Hu Mo Rt
Immunogen：Synthetic peptide corresponding to C-EQKDSDNYRVFER, from human TXNDC4, at the internal region of the protein (NP_055866.1).
