STAM2 (signal transducing adapter molecule 2), a ubiquitously expressed protein and member of the STAM family, involved in cytokine-mediated signal transduction, downstream of JAK kinases.
STAM2 is involved in mediating the endocytic sorting of ubiquitinated membrane proteins on early endosomes, binding directly with ubiquitin, and co-localizing with Hrs (hepatocyte growth factor-regulated tyrosine kinase substrate) and Eps15 (epidermal growth factor receptor substrate 15), in clathrin-containing endosomal microdomains.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:8000Western Blot: 1-3ug/ml, observed in human spleen lysates on ~70kD bandsOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity：Recognizes human STAM2. Species sequence homology: Canine and mouse.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Ca Hu Mo
Immunogen：Synthetic peptide corresponding to C-QSIDPTDSKPDSQD, from human STAM2, at the internal region of the protein (NP_005834.3).
