Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4.
Does not act on PRDX5 or PRDX6.
May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase.
Applications:Suitable for use in ELISA and Western Blot.
A band of ~16kD was observed in human colon and kidney lysatesOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Specificity:Recognizes human SRX1.
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Bo Hu Mo Po Rt
Immunogen:Synthetic peptide corresponding to C-KVQSLVDTIREDPD at the internal region of human SRX1 (NP_542763.1). Species sequence homology: bovine, mouse, porcine, rat