Likely to be a multifunctional endocytic receptor, that may be implicated in the uptake of lipoproteins and of proteases.
Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis.
Binds the receptor-associated protein (RAP).
Could play a role in cell-cell interaction.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:32,000Western Blot: 0.3-1ug/ml, observed in mouse and rat brain lysates on ~250kD bandsOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity：Recognizes mouse SORL1. Species sequence homology: Bovine, canine, human and rat.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Bo Ca Hu Mo Rt
Immunogen：Synthetic peptide corresponding to C-TGFSDDVPMVIA, from mouse SORL1, at C-terminal (NP_003096.1).
