84-1231-12　SLC4A8 (Electroneutral Sodium Bicarbonate Exchanger 1, Electroneutral Na(+)-Driven Cl-HCO3 Exchanger, Solute Carrier Family 4 Member 8, k-NBC3, KIAA0739, NBC, NBC3, NDCBE1) 100ug　S1014-24A

特徴

• Mediates electroneutral sodium- and carbonate-dependent chloride-HCO3- exchange with a Na+:HCO3- stoichiometry of 2:1.
• Plays a major role in pH regulation in neurons.
• May be involved in cell pH regulation by transporting HCO3- from blood to cell.
• Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3- into the cells.
• Also mediates lithium-dependent HCO3- cotransport.
• May be regulated by osmolarity.
• Applications:Suitable for use in ELISA.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:1000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for at least 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.