This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen.
This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons.
It is a cation-specific, but otherwise relatively nonselective, ion channel.
Applications:Suitable for use in ELISA, Immunocytochemistry, Immunofluorescence and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:128,000Western Blot: 0.3-1ug/ml, observed in human colon lysates on ~55kD bandsOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity:Recognizes HTR3A. Species Crossreactivity: Human and rat.
Isotype:IgG
Calc Applications Abbrev:E IC IF WB
Calc Crossreactivity:Hu Rt
Immunogen:Synthetic peptide corresponding to C-GPQDFEKSPRDR, from HTR3A, at the internal region of the protein (NP_998786.2, NP_000860.2, NP_001155244.1).