In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components.
Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA).
May also play a role in vesicular trafficking.
Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:128,000Western Blot: 0.01-0.03ug/ml, observed in lysates of cell lines HEK293 and A431 on ~28-30kD bandsOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity：Recognizes human SDCBP. Species sequence homology: Canine, mouse and rat.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Ca Hu Mo Rt
Immunogen：Synthetic peptide corresponding to SLEDLKVDKVIQAQ-C, from human SDCBP, at N-terminal (NP_005616.2, NP_001007068.1).
